Cannabidiol, commonly known as CBD, is one of the main components of hemp cannabis sativa L. It is probably one of the most studied cannabinoids by scientists after THC.
The Cannabis Sativa L. plant originating from Asia was already cultivated in the Neolithic period for its medicinal properties, its textile fibres and its seeds. Its use has continued over the centuries but its exact composition has long remained unknown. Cannabinoids, molecules present in the Cannabaceae, were discovered at the beginning of the 20th century.
Cannabidiol is believed to have been extracted and isolated in laboratories in the United States in the 1940s. It is one of the major constituents of hemp. It was discovered almost 20 years before the very controversial THC. The study of these two phytocannabinoids has allowed to think about their use in pharmacology.
Cannabis Sativa L contains more than 400 phytocannabinoids, 80 of which have not been found in any other plant. For obvious reasons, research has focused on THC, the most psychotropic of the phytocannabinoids. Phytocannabinoids interact in our bodies with a vast network of receptors called the endocannabinoid system. The chemical compounds or cannabinoids that are created by our bodies are called endocannabinoids.
The endocannabinoid system plays an essential role in regulating our mood, appetite and immune response. It influences our immune response, our ability to fight stress and pain.
The first studies on cannabidiol (CBD) were conducted in the 1940s. They were already showing its positive effects on anxiety. Later, other studies showed its benefits on nausea and pain. More recently, researchers have discovered that it reduces the degeneration of neurons and that it could perhaps be used in the treatment of Alzheimer's disease.
Medical research shows a particular interest in this molecule because it has numerous therapeutic properties. Non-addictive, and showing very few side effects, CBD has an interesting effect on inflammation in general. It would be effective against pain related to arthritis;
Not psychotropic, CBD is an anxyolitic. It can act on anxiety disorders and depression in general. It is also effective for certain forms of epilepsy, especially in children such as Dravet's syndrome or Lennox-Gastaut syndrome.
It is also found in the composition of the drug Sativex, to relieve spasms related to multiple sclerosis.
CBD has become also a leading ingredient in cosmetology for its anti-inflammatory and antiseptic properties and has been used in dermatology practices to treat acne and psoriasis. Major cannabidiol studies are still underway around the world. In combination with other cannabinoids, CBD holds great promise in the medical world for serious diseases such as autoimmune diseases, cancer and diabetes.